Having thus far perfected the instrument, I wrote to the chief officer of the Metropolitan Fire Brigade, asking him whether such a respirator would be of use to him. His reply was prompt; it would be most valuable. He had, however, made himself acquainted with every contrivance of the kind in this and other countries, and had found none of them of any practical use. He offered to come and test it here, or to place a room at my disposal in the City. At my request he came here, accompanied by three of his men. Our small room was filled with smoke to their entire satisfaction. The three men went successively into it, and remained there as long as Captain Shaw wished them. On coming out they said that they had not suffered the slightest inconvenience; that they could have remained all day in the smoke. Captain Shaw then tested the respirator with the same result, and he afterwards took great interest in the perfecting of the instrument.

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Various ameliorations and improvements have recently been introduced into the smoke respirator. The hood of Captain Shaw has been improved upon by the simple and less expensive mouthpiece of Mr. Sinclair; and this, in its turn, has been simplified and improved by my assistant Mr. John Cottrell. The respirator is now in considerable demand, and it has already done good practical service. Care is, however, necessary, in moistening the wool with glycerine. It must be carefully teazed, so that the individual fibres may be moistened, and clots must be avoided. I cannot recommend the layers of moistened flannel which, in some cases, have been used instead of cotton-wool: nothing equals the wool, when carefully treated.

An experiment made last year brought out very conspicuously the necessity of careful packing, and the enormous comparative power of resisting smoke irritation possessed by our firemen, and the able officer who commands them. Having heard from Captain Shaw that, in some recent very trying experiments, he had obtained the best effects from dry cotton-wool, and thinking that I could not have been mistaken in my first results, which proved the dry so much inferior to the moistened wool and its associated charcoal, I proposed to Captain Shaw to bring the matter to a test at his workshops in the City. He was good enough to accept my proposal, and thither I went on May 7, 1874. The smoke was generated in a confined space from wet straw, and it was certainly very diabolical.

At this season of the year I am usually somewhat shorn of vigour, and therefore not in the best condition for severe experiments; still I wished to test the matter in my own person. With a respirator which had been in use some days previously, and which was not carefully packed, I followed a fireman into the smoke, he being provided with a dry-wool respirator. I was compelled to quit the place in about three minutes, while the fireman remained there for six or seven minutes.

I then tried his respirator upon myself, and found that with it I could not remain more than a minute in the smoke; in fact the first inhalation provoked coughing.

Thinking that Captain Shaw himself might have lungs more like mine than those of his fireman, I proposed that we should try the respirators together; but he informed me that his lungs were very strong. He was, however, good enough to accede to my request. Before entering the den a second time I repacked my respirator, with due care, and entered the smoke in company with Captain Shaw. I could hear him breathe long slow inhalations; his labour was certainly greater than mine, and after the lapse of seven minutes I heard him cough. In seven and a half minutes he had to quit the place, thus proving that his lungs were able to endure the irritation seven times as long as mine could bear it. I continued in the smoke, with hardly any discomfort, for sixteen minutes, and certainly could have remained in it much longer. The advantage arising from the glycerine was thus placed beyond question.

During this time I was in a condition to render very material assistance to a person in danger of suffocation.

[Helmholtz on Hay Fever.]

In my lecture on Dust and Disease in 1870, I referred to an experiment made by Helmholtz upon himself which strikingly connected hay fever with animalcular life. About a year ago I received from Professor Binz of Bonn a short, but important paper, embracing Helmholtz's account of his observation, to which Professor Binz has added some remarks of his own. The paper, being mainly intended for English medical men, was published in English, and though here and there its style might be amended, I think it better to publish it unaltered.