The archeus of Van Helmont, like that of Paracelsus, has its seat in the stomach. It is the same thing as the sentient soul. This notion of the nature and seat of the archeus was founded on the following experiment: He swallowed a quantity of aconitum (henbane). In two hours he experienced the most disagreeable sensation in his stomach. His feeling and understanding seemed to be concentrated in that organ, for he had no longer the free use of his mental faculties. This feeling induced him to place the seat of understanding in the stomach, of volition in the heart, and of memory in the brain. The faculty of desire, to which the ancients had assigned the liver as its organ, he placed in the spleen. What confirmed him still more in the idea that the stomach is the seat of the soul, is the fact, that life sometimes continues after the destruction of the brain, but never, he alleges, after that of the stomach. The sentient soul acts constantly by means of the vital spirits, which are of a resplendent nature, and the nerves serve merely to moisten these spirits which constitute the mediums of sensation. By virtue of the archeus man is much nearer to the realm of spirits and the father of all the genii, than to the world. He thinks that Paracelsus’s constant comparison of the human body with the world is absurd. Yet Van Helmont, at least in his youth, was a believer in magnetism, which he employed as a method of explaining the effect of sympathy.

The archeus exercises the greatest influence on digestion, and he has chiefly the stomach and spleen under his superintendence. These two organs form a duumvirate in the body; for the stomach cannot act alone and without the concurrence of the spleen. Digestion is produced by means of an acid liquor, which dissolves the food, under the superintendence of the archeus. Van Helmont assures us that he had himself tasted this acid liquor in the stomach of birds. Heat, strictly speaking, does not favour digestion; for we see no increase of the digestive powers during the most ardent fever. Nor are the powers of digestion wanting in fishes, although they want the animal heat which is requisite for mammiferous animals. Certain birds even digest fragments of glass, which, certainly, simple heat would not enable them to do. The pylorus is, in some measure, the director of digestion. It acts by a peculiar and immaterial power, in virtue of a blas, and not as a muscle. It opens and shuts the stomach according to the orders of the archeus. It is in it, therefore, that the causes of derangement of digestion must be sought for.

The duumvirate just spoken of is the cause of natural sleep, which does not belong to the soul, as far as it resides in the stomach. Sleep is a natural action, and one of the first vital actions. Hence the reason why the embryo sleeps without ceasing. At any rate it is not true that sleep is owing to vapours which mount to the brain. During sleep the soul is naturally occupied, and it is then that the deity approaches most intimately to man. Accordingly, Van Helmont informs us, that he received in dreams the revelation of several secrets, which he could not have learnt otherwise.

The duumvirate operates the first digestion, of which, Van Helmont enumerates six different species. When the acid, which is prepared for digestion, passes into the duodenum it is neutralized by the bile of the gall-bladder. This constitutes the second digestion. To the bile of the gall-bladder, Van Helmont gave the name of fel, and he carefully distinguished it from the biliary principle in the mass of the blood. This last he called bile. The fel is not an excrementitious matter, but a humour necessary to life, a true vital balsam. Van Helmont endeavoured to show by various experiments that it is not bitter.

The third digestion takes place in the vessels of the mesentery, into which the gall-bladder sends the prepared fluid. The fourth digestion is operated in the heart, where the red blood becomes more yellow and more volatile by the addition of the vital spirits. This is owing to the passage of the vital spirit from the posterior to the anterior ventricle, through the pores of the septum. At the same time the pulse is produced, which of itself develops heat; but does not regulate it in any manner, as the ancients pretended that it did. The fifth digestion consists in the conversion of the arterial blood into vital spirit. It takes place principally in the brain, but is produced also throughout all the body. The sixth digestion consists in the elaboration of the nutritive principle in each member, where the archeus prepares its own nourishment by means of the vital spirits. Thus, there are six digestions: the number seven has been chosen by nature for a state of repose.

From the preceding sketch of the physiology of Van Helmont, it is evident that he paid little or no regard to the structure of the parts in explaining the functions. In his pathology we find the same passion for spiritualism. He admitted, indeed, the importance of anatomy, but he regretted that the pathological part of that science had been so little cultivated. As the archeus is the foundation of life and of all the functions, it is plain that the diseases can neither be derived from the four cardinal humours, nor from the disposition or the action of opposite things; the proximate cause of diseases must be sought for in the sufferings, the anger, the fear, and the other affections of the archeus, and their remote cause may be considered as the ideal seed of the archeus. Disease, in his opinion, is not a negative state or a mere absence of health, it is a substantial and active thing as well as a state of health. Most of the diseases which attack certain parts or members of the body result from an error in the archeus, who sends his ferment from the stomach in which he resides into the other parts of the body. Van Helmont explained in this way not only the epilepsy and madness, but likewise the gout, which does not proceed from a flux, and has not its seat in the limb in which the pain resides, but is always owing to an error in the vital spirit. It is true that the character of the gout acts upon the semen in which the vital spirit principally manifests its action, and that in this way diseases are propagated in the act of generation; but if, during life instead of altering the semen it is carried to the liquid of the articulations, this is a proof of the prudence of nature, which lavishes all her cares on the preservation of the species, and loves better to alter the humours of the articulations than the semen itself. The gout acidifies the liquors of the articulations, which is then coagulated by the acids. The duumvirate is the cause of apoplexy, vertigo, and particularly of a species of asthma, which Van Helmont calls caducus pulmonalis. Pleurisy is produced in a similar way. The archeus, in a movement of rage, sends acrid acids to the lungs, which occasion an inflammation. Dropsy is also owing to the anger of the archeus, who prevents the secretions of the kidneys from going on in the usual way.

Of all the diseases, fever appeared to him most conformable to his notions of the unlimited power of the archeus. The causes of fever are all much more proper to offend the archeus, than to alter the structure of parts and the mixture of humours. The cold fit is owing to a state of fear and consternation, into which the archeus is thrown, and the hot stage results from his disordered movements. All fevers have their peculiar seat in the duumvirate.

Van Helmont was in general much more successful in refuting the scholastic opinions by which the practice of medicine was regulated in his time, than in establishing his own. We are struck with the force of his arguments against the Galenical doctrine of fever, and against the influence of the cardinal humours on the different kinds of fever. He refuted no less vehemently the idea of the putridity of the blood, while that liquid circulates in the vessels. Perhaps he carried the opposite doctrine too far; but his opinions have had a good effect upon subsequent medical theory, and medical men learned from them to make less use of the term putridity. The phrase mixture of humours, not more intelligible, however, came to be substituted for it.

Van Helmont’s theory of urinary calculi deserves peculiar attention, because it exhibits the germ of a more rational explanation of these concretions than had been previously attempted by physiologists. Van Helmont was aware that Paracelsus, who ascribed these concretions to tartar, had formed an idea of their nature, which a careful chemical analysis would immediately refute. He satisfied himself that urinary calculi differ completely from common stones, and that they do not exist in the food or drink which the calculous person had taken. Tartar, he says, precipitates from wine, not as an earth, but as a crystallized salt. In like manner, the natural salt of urine precipitates from that liquid, and gives origin to calculi. We may imitate this natural process by mixing spirit of urine with rectified alcohol. Immediately an offa alba is precipitated.

It is needless to observe that Van Helmont was mistaken, in supposing that this offa was the matter of calculus. Spirit of urine was a strong solution of carbonate of ammonia. The alcohol precipitated this salt; so that his offa was merely carbonate of ammonia. Nor is there the shadow of evidence that alcohol, as Van Helmont thought it did, ever makes its way into the mass of humours; yet his notion of the origin of calculi is not less accurate, though of course he was ignorant of the chemical nature of the various substances which constitute these calculi. From this reasoning Van Helmont was induced to reject the term tartar, employed by Paracelsus. To avoid all false interpretations he substitutes the word duelech, to denote the state in which the spirit of urine precipitates and gives origin to these calculous concretions.