91 Lahmung der Kinder, p. —.
92 Jahrb. f. Kinderheilk., 1865.
93 Reynolds's Syst. of Medicine.
The first really modern autopsy, that made by Cornil in 1863, agrees with the two earliest on record in disclosing only an atrophy of the cord. Some of the other cases, contained in Table III., note in addition sclerosis of the lateral columns.
In all the remaining autopsies on record are noted atrophy of the anterior gray cornua and more or less extensive destruction of the ganglionic cells.
In a certain number of cases the atrophy seemed to be the unique lesion. But it never was confined to the ganglionic cells, but included the reticulum of gray fibres in which these were imbedded, and which was replaced by a reticulum of connective tissue. These cases were all examined many years after the occurrence of the paralysis.
TABLE III.—AUTOPSIES SHOWING ATROPHY OR SCLEROSIS OF WHITE COLUMNS OR ROOTS.
| No. | Year. | Name of Author and Patient. | Age at time of Paralysis. | Age at time of Autopsy. | Nature of Symptoms. | Limbs Paralyzed. | Electric Reaction. | Appearance at Autopsy. | Reference in Literature. |
| 10 | 1825 | Hutin. | 7 | 49 | Convulsions. | b. u. | ? | Atrophy of cord from below 8th dorsal nerve to thickness pencil, and of nerves. | Quoted by Heine, p. 151. |
| 11 | 1842 | Lunget. | ? | 8 | ? | r. u. | ? | Atrophy and brown discol. of ant. roots of lumbar and sacral nerves going to sciatic. | Anat. et Phys. du Syst. nerveux, i. p. 358. |
| 12 | 1863 | Reckling- hausen. | ? | ? | ? | b. u. | ? | Atrophy of ant.-lateral columns. | Deutsche Klinik, 1863, Jan. 3. Seel. says also atrophy of cells; Seguin and J., tubercles. |
| 13 | 1863 | Cornil. | 2 | 49 | ? | b. u. | ? | Atrophy antero-lateral columns. Seeligmüller says also atrophy of ganglion-cells, as if quoting Charcot. | Soc. de Biol., Comptes Rendus, 1863. Infiltration of gray and white corpuscles, with abundant amyloid corpuscles, especially in anterior gray cornua. These through entire extent of cord—cells—intact. Paraplegia, but walks by muscles of thigh and pelvis; leg and foot atrophied. |
| 14 | 1864 | Laborde and Bouvier. | 1 | 2 | ? | all four. | noted. | Atrophy antero-lateral columns; nerve-fibres atrophied and varicose. | Laborde, De la Paralysie de l'Enfance, pp. 109-119. |
| 15 | 1864 | Laborde and Cornil. | ⅔ | 2 | ? | b. u. | ? | Sclerosis of ant.-lateral columns. Ganglion-cells normal; sciatic neuritis. | Laborde, loc. cit., p. 104. |
The first group is contained in the following table:
TABLE IV.—AUTOPSIES SHOWING ATROPHY OF THE ANTERIOR CORNUA AND GANGLION-CELLS.