The essence of vitalism, so Bunge would have it, lies in starting from what we know, the internal world, to explain what we do not know, the external world. We can only remark that this position appears to rest upon an epistemological confusion, for Bunge has evidently failed to distinguish between the idealism which teaches that the world of nature, including our own bodies, only exists in so far as it is an object of knowledge, that reality is ultimately ideal, and the ‘animism’ which, as we have seen, gives every object, at least every living object, in nature a directive consciousness of its own. The former does not lie immediately within the scope of the present inquiry; the latter we shall have occasion to discuss again.

How far the tenets of animism are to be attributed to Johannes Müller is not very clear. For while Müller maintained that an organism is due to an idea which regulates its structure, is the cause of its harmony, and is in action in the organism itself, exerting on it a formative power, yet he held that the process was unconscious. Müller indeed distinguished explicitly between the vital and the mental or conscious principle, for in the operations of the former the manifestation of design is the result of necessity, not of choice. At the same time the two resemble one another in being homogeneous, in existing throughout the mass of the organism which they animate, and in being divided together with the organism (as in regeneration) without suffering any diminution or change of their powers.

In this conception of the unconscious idea there may possibly be some confusion between the formal and the final cause, between the idea of the end to be realized, present at the beginning in the mind of the artificer, and the end itself. The former is animism: the latter is sound enough as metaphysics, but is not science at all.

There is still another school of vitalists which, while not going so far as to commit itself to a belief in a ‘psychoid’, yet proclaims in no uncertain voice the autonomy of the organism, and not content with the assertion that at present we have not succeeded in reducing the activities of the organism to chemical, physical, and mechanical processes, maintains the utter futility of such endeavour, and pronounces over the hidden mysteries of life an eternal Ignorabimus.

Some such view as this we must, I think, attribute to Dr. Haldane. ‘In biology’, he says, ‘the phenomena which are or ought to be observed from the very beginning are not physical and chemical phenomena as self-​existent events, but these phenomena as expressions of the activity of living organisms. It is the living organism, and not the physical phenomenon, which is the reality for biology.’ His belief in organic autonomy is based on the physiology of metabolism, secretion and absorption, the circulation of the blood, and the nervous system. Thus in discussing the blood, after pointing to the constancy in its volume and composition, he proceeds: ‘Neither starvation nor ingestion of food and drink materially affect it: liquid injected into it is got rid of with remarkable rapidity; and any loss of blood by bleeding is soon replaced. This vital metabolism of the circulatory system is doubtless due chiefly to the activity of its lining endothelium, which most certainly does not play the mere mechanical part which has often been attributed to it. The other so-called “mechanisms” can likewise be shown to have all the characteristics of the living body, inasmuch as they actively maintain their structure, just as the organism as a whole does so. There is thus no warrant for calling them mechanisms, and thus ignoring what is one of their essential characteristics.’ In passages such as these we seem to catch an echo of Müller’s unconscious idea, and again we ask ourselves, Are we dealing with a final or a formal cause? Indeed, Dr. Haldane insists that his ground conception is teleological.

There is still one other vitalistic theory to which we must allude, although its interest is now merely historical. This is the belief in a special vital material, unlike the material of which lifeless bodies are composed, and endowed with a special vital force, different from but co-ordinate with the forces of mechanics and physics.

In his Histoire Générale des Animaux Buffon, after referring to the obvious peculiarities of animals and vegetables—that their actions are directed to an end, the conservation of a durable species—proceeds to elaborate a thesis in which it is held that they are composed of organic germs, and that germs of the same kind are distributed throughout nature, lifeless as well as living. When an animal or plant dies, its body is dissolved into these germs, which are then scattered abroad; when it assimilates, it is by separating these ubiquitous particles from the brute inorganic portion of the food. The former is utilized for its own growth, the latter it gets rid of by evacuation and excretion. Lifeless matter is therefore never converted into living material.

Another advocate of the doctrine of a vital force, a property of the tissues of the body, and at perpetual war with those inorganic forms which tend to their destruction, was the physiologist Bichat, Such a conception as this could not of course survive the rise of modern chemistry. Its death-​knell was sounded when Lavoisier and Laplace showed that the bodies of organisms were composed of the same elements as are found in inanimate nature, and it has long since passed into the limbo of discredited speculations.

Apart from this, vitalistic theories would appear to be in the main of two kinds.