In 1507 it appeared at Venice in small black-letter quarto as Opera noua intitulata Il perche utilissima ad intendere la cagione de molte cose. By this title, Il Perchè, the work, which ran through numerous editions, has usually been known. It continued to be reprinted as late as 1668.
(c) A treatise on the Plague: Tractate degno & utile de la pestile[n]tia co[m]posto p[er] el famosissimo philosopho medico & astrologo maestro Hieronymo di manfredi da Bologna, Bologna, 1478. This was translated into Latin by the author himself in the same year. The work owes much to Avicenna, but contains some original clinical observations, and shows a certain independence of the prevailing spirit of the age by quoting opinions of contemporary as well as of ancient physicians. The remedies are similar to those recommended by John of Bourdeaux in his widely distributed tract on the plague, and are probably derived ultimately from the Regimen Sanitatis Salerni.
(d) Prognosticon ad annum 1479, Bologna, 1478. We reproduce the terminal page of this work (Fig. 10).
Fig. 10. The last page of Manfredi’s Prognosticon ad annum 1479, Bologna, 1478.
From his tomb in the Church of S. Giacomo Maggiore at Bologna
Plate XXXVII. GIOVANNI BENTIVOGLIO II