1573 Venice is forced to make peace with the Turks. She gives up Cyprus and pays a large tribute.

1575 The emperor acknowledges the title of grand duke of Tuscany.

1576 Great devastation made by the plague in Italy.

1578 Failure of a conspiracy at Florence against the grand duke of Tuscany.

1580 Charles Emmanuel succeeds his father as duke of Savoy.

1582 Charles Emmanuel fails in an attempt to capture Genoa.

1586 Death of Ottavio Farnese, duke of Parma. His son Alessandro succeeds.

1588 The duke of Savoy taking advantage of Francis’ distracted condition, conquers Saluzzo.

1589 The duke of Savoy invades Provence.

1590 The French drive Charles Emmanuel from Provence.