1528 The French besiege Naples, but are driven by disease to retreat.

1529 Battle of Landriano. Spaniards defeat the French. Francis Pizarro commissioned to conquer and govern Peru. Treaty of Cambray called “The Ladies’ Peace.” Francis I agrees to ransom his sons and resign his pretensions to Flanders, Artois, and all places in Italy. Charles goes to Italy, makes peace with Venice, and with the dukes of Milan and Ferrara.

1530 Charles receives the iron crown of Lombardy and is crowned emperor by the pope. Florence taken. Charles makes Alessandro de’ Medici its absolute ruler. He summons the Diet of Augsburg to settle religious questions and prepare for war with the Turks.

1531 Ferdinand, brother of Charles, elected king of the Romans.

1533 Pizarro establishes his authority in the capital of Peru.

1535 Expedition to Tunis in conjunction with Portugal, Genoa, the pope, and the knights of Malta. The usurper Barbarossa is expelled and the king Mulei Hassan restored as a vassal of Spain. Ten thousand Christian slaves released. Francis I invades Savoy. Its duke appeals to Charles. Death of the duke of Milan. Charles takes possession of the duchy. Colony of Buenos Ayres founded by Pedro de Mendoza.

1536 Francis occupies Piedmont. Provence invaded by Charles, who finds it already desolated by the French, and retreats in disorder.

1537 French invasion of the Netherlands. Truce with France.

1538 It is extended for ten years (Truce of Nice). Mutiny amongst Charles’ troops in Milan, Sicily, and Africa. Their generals borrow money to pacify them. Cortes of Toledo. The deputies protest against the extravagance of Charles’ foreign wars, and the nobles claim their privilege of exemption from taxation. Charles dismisses the estates. This was the last occasion on which nobles and prelates were summoned. The cortes was henceforth reduced to a meeting of the deputies of eighteen cities.