Bodæus à Stapel, in his comment upon Theophrastus[15], tells us of two youths, that eat two or three of these berries, which they got in the Leyden garden, mistaking them for black currants: one of them perished, and the other recovered with great difficulty.
Simon Pauli relates two or three examples to the same effect[16]. Wepfer gives us a circumstantial account of a child about ten years old, who was thrown into a great variety of convulsive symptoms after eating of this fruit: but proper care being taken by vomiting, and afterwards giving alexipharmics and anti-epileptic medicines, he recovered[17].
M. Boulduc[18] laid before the Royal Academy of Sciences at Paris, the case of some children, who, upon eating these berries, were seized with a violent fever, palpitations of the heart, convulsions, and lost their senses. One of them, a little boy of four years old, died the next morning.
Boerhaave has instances to the same effect[19]: and it was the misfortune of Dr. Abraham Munting, a noted botanist and professor of physic in the university of Groningen, to have his own daughter poisoned with the berries of the Bella-donna.
It would be almost endless to recite all the instances to be met with upon this head. The German Ephemerides, the Commercium Literarium, and other periodical works, furnish us with farther proofs of the deadly quality of the Bella-donna; and they are unhappily corroborated by more recent instances in modern authors. The Gentleman's Magazine[20], Mr. Miller in his Gardeners Dictionary, and Dr. Hill in his British Herbal[21], exhibit to us several melancholy cases of this kind.
The effects of this plant have been so extraordinary, that several distinct treatises have been published professedly upon it. The most remarkable of these is that of J.M. Faber's, printed at Augsburg in 1677, under the following title; Strychnomania explicans Strychni manici antiquorum, vel Solani furiosi recentiorum historiam. In this tract the author has collected a number of cases from various hands, concerning the poisonous quality of the plant in question. In the year 1714. C. Sicelius published a treatise upon this plant, under the title of Diatribe de Bella-donna. Jenæ. 8vo.
Medical History.
Who it was, that was bold enough to venture first upon the internal use of this plant as a medicine, I cannot say; chance very probably led to it, as in many other cases. In the mean time, there is reason to believe, that it is not altogether a modern practice. One would be led to think, by the accounts given us in Matthiolus and Bodæus, that in their days its operation was very well known; and that they knew how to dose it very exactly, since they give us an account of tricks being played with it, by infusing the quantity of a scruple of the root in wine, and intoxicating people therewith. The former of these authors relates, that the distilled water from this plant, in a dose of about two or three spoonfuls, was exhibited by some people in inflammations of the viscera; and, he observes, with good success. Parkinson seems to have transcribed this account, respecting this use of it; but neither of them speak of it from their own knowlege. It may be questioned, however, whether this could act otherwise than as mere water; since the principles with which this plant is endued, do not seem capable (if one may judge from its sensible qualities and effects upon those who have taken it) of rising in a still.
Mr. Ray[22], from the German Ephemerides, an. 13. obs. 64. presents us with the relation of a shepherd in Denmark, who administered an infusion of the berries in wine in the dysentery, which was there very common, and very obstinate; adding, that it was attended with great success, not only restraining the flux, but carrying off the disorder by sweat. Mr. Ray observes further, that, correspondent with this practice, Conrade Gesner actually prepared a syrop from the berries, and gave it in dysenteric cases with great success. This account is found in Gesner's Epistles, and is quoted also by Dr. Haller[23], when treating of this plant. Possibly its efficacy in these cases may be accounted for, from considering it merely in the quality of an opiate; and therefore it cannot be adviseable to use it, when safer medicines are always at hand.
Its external use seems to be of as long a date as its internal; and it was on account of its cooling and repellent quality, that it came into credit as a fucus among the Italian ladies. Matthiolus recommends it in the erysipelas, the shingles, and other inflammatory disorders of the skin. The leaves, applied in the form of a cataplasm, are much celebrated by many writers, as of great use in resolving tumors, particularly of the breast, and even such as are of a schirrous and cancerous nature. Many of the old authors[24] mention this application of it, among other of the cooling and narcotic herbs; such as the common nightshade, henbane, hounds-tongue, &c. which it was usual to apply on such occasions. Mr. Ray informs us, that Mr. Percival Willughby experienced its efficacy repeatedly, in discussing hardnesses and cancerous tumors in the breast.