Its relaxing quality is very surprising, as appears by that memorable case related by the last-mentioned author, of a lady's applying a leaf of it to a little ulcer, suspected to be of the cancerous kind, a little below her eye, which rendered the pupil so paralytic, that it lost all its motion for some time afterwards: and that this event was really owing to that application, appears from the experiment's being repeated with the same effect three times.
The German physicians have gone much further: they have even ventured to give it inwardly in cancerous cases. Dr. Haller, when treating of the quality of this plant, refers to Junker, and others of the modern physicians, as recommending the decoction of it with caution, that it be not given in such quantity as to cause sleep. So long since as the year 1739. there was a thesis published at Hall, by Michael Albert, in which the Bella-donna is proposed as a specific in cancerous cases. What other physicians patronize this use of it, I cannot say, having but little opportunity of consulting those academic pieces, which are of such eminent use in compilations of this kind. Thus much is certain, that its use, in such cases, rather gains ground; and the case, published in the French Bibliotheque[25], printed at the Hague, of an ulcerated cancer being radically cured by an infusion of the leaves of this plant in water, deserves particular attention, on account of its being so well attested. The case is extracted from an inaugural thesis of Professor Lambergen's, who was the physician concerned[26]. The event was so singularly happy and successful in this instance, that we hope it will need no apology, if we give a particular detail of it.
The person afflicted with this miserable disease was a widow of 34 years of age, and mother of four children. She had but weak nerves, and had been subject to inflammatory disorders. She informed M. Lambergen, upon examining her, that she had had a quinzy six times, which had twice ended in suppuration: that eight years before her right breast had suppurated, and discharged much matter: that two years after it suppurated again; and that at the end of another year both breasts underwent the same fate; since when the right had remained schirrous, but was without pain, except when she handled it. She had suckled her youngest child about six months, when she was seized with a fever; and the left breast (with which only she could suckle since the other had suppurated) soon swelled, inflamed greatly, was very painful, and soon became almost as large as a child's head. Dr. Lambergen being called in, ordered copious bleeding, and that the child should suck as little as possible. She took some medicines, and soon recovered.
A year passed after this without any bad accident; when the lunar evacuations, which she had had from her 18th year, beginning to diminish, she felt a pricking pain in her left breast, and her right began to swell. Upon a fright, she had a fall, which accident increased both the pain and swelling; and she had recourse again to Dr. Lambergen.
He found the tumors in her right breast much enlarged, and so connected together, as to feel like one large one only. On the upper part of the breast, upon the pectoral muscle, it felt rugged, unequal, and almost as hard as a stone. The patient complained of a constant itching in the part, and at times a pungent pain, which seemed to shoot from the armpit, and end in the tumor. Under this armpit the glands were hard and schirrous; and the left breast was not exempt from the like indurations. A vein or two on the right breast was a little enlarged, otherwise no alteration. It was no hotter than common; nor had it undergone any change of colour. To mitigate the pain of the schirrous, Dr. Lambergen ordered the following plaister:
℞ Ung. Diapomphol. ℥ ij. Amalgam, merc. et Plumb. ȝ iij. Sperm. Cet. ȝ j. M.
With this external application he prescribed likewise the following powders, to be taken night and morning, and gave directions relating to the non-naturals.
℞ Coral. rub. Antimon. Diaphoret. illot. Sper. Ceti a ȝ ij. Laud. gr. vj. M. for 12 doses.
Under this method the pain remitted, but the tumor inlarged, and a little rising was observed on the upper part of it; and towards the nipple, where there was the least hardness, a small spot was perceived, which, at the next return of the catamenia, inflamed, and became the seat of the most excruciating pain. Dr. Lambergen, during this period, in the room of the powders, substituted emmenagogic pills, and ordered the pediluvium. She lost ten ounces of blood from the foot: and by these means the swelling of the breast diminished, and the patient suffered very little for some days. This truce, however, was but temporary: the rising on the upper part of the tumor began to inflame, itched intolerably, the pain returned, was almost perpetual, and insupportably pungent.
In this dreadful state was the patient, when Dr. Lambergen desired the late Dr. du Bois, Dr. Winter, physician to the house of Orange and professor at Leyden, together with Dr. Van Arum of Leewarden, physician in ordinary to the Princess dowager, to visit her. These gentlemen examined her many times, and unanimously agreed, that it was now no less than a confirmed cancer. It was Professor Winter, who acquainted Dr. Lambergen, that he had heard M. Degner, a celebrated physician at Nimeguen, speak of the Bella-donna, as a sovereign remedy against inveterate schirri; adding, nevertheless, that he had never tried it himself.