ERYSIPELAS (a Greek word, probably derived from ἐρυθρός, red, and πέλλα, skin)—synonyms, the Rose, St Anthony’s Fire—an acute contagious disease, characterized by a special inflammation of the skin, caused by a streptococcus. Erysipelas is endemic in most countries, and epidemic at certain seasons, particularly the spring of the year. The poison is not very virulent, but it certainly can be conveyed by bedding and the clothes of a third person. Two varieties are occasionally described, a traumatic and an idiopathic, but the disease seems to depend in all cases upon the existence of a wound or abrasion. In the so-called idiopathic variety, of which facial erysipelas is the best known, the point of entry is probably an abrasion by the lachrymal duct.
When the erysipelas is of moderate character there is simply a redness of the integument, which feels somewhat hard and thickened, and upon which there often appear small vesications. This redness, though at first circumscribed, tends to spread and affect the neighbouring sound skin, until an entire limb or a large area of the body may become involved in the inflammatory process. There is usually considerable pain, with heat and tingling in the affected part. As the disease advances the portions of skin first attacked become less inflamed, and exhibit a yellowish appearance, which is followed by slight desquamation of the cuticle. The inflammation in general gradually disappears. Sometimes, however, it breaks out again, and passes over the area originally affected the second time. But besides the skin, the subjacent tissues may become involved in the inflammation, and give rise to the formation of pus. This is termed phlegmonous erysipelas, and is much more apt to occur in connexion with the traumatic variety of the disease. Occasionally the affected parts become gangrenous. Certain complications are apt to arise in erysipelas affecting the surface of the body, particularly inflammation of serous membranes, such as the pericardium or pleura.
Erysipelas of the face usually begins with symptoms of general illness, the patient feeling languid, drowsy and sick, while frequently there is a distinct rigor followed with fever. Sore throat is sometimes felt, but in general the first indication of the local affection is a red and painful spot at the side of the nose or on one of the cheeks or ears. Occasionally it would appear that the inflammation begins in the throat, and reaches the face through the nasal fossae. The redness gradually spreads over the whole surface of the face, and is accompanied with swelling, which in the lax tissues of the cheeks and eyelids is so great that the features soon become obliterated and the countenance wears a hideous expression. Advancing over the scalp, the disease may invade the neck and pass on to the trunk, but in general the inflammation remains confined to the face and head. While the disease progresses, besides the pain, tenderness and heat of the affected parts, the constitutional symptoms are very severe. The temperature rises often to 105° or higher, remains high for four or five days, and then falls by crisis. Delirium is a frequent accompaniment. The attack in general lasts for a week or ten days, during which the inflammation subsides in the parts of the skin first attacked, while it spreads onwards in other directions, and after it has passed away there is, as already observed, some slight desquamation of the cuticle.
Although in general the termination is favourable, serious and occasionally fatal results follow from inflammation of the membranes of the brain, and in some rare instances sudden death has occurred from suffocation arising from oedema glottidis, the inflammatory action having spread into and extensively involved the throat. One attack of this disease, so far from protecting from, appears rather to predispose to others. It is sometimes a complication in certain forms of exhausting disease, such as phthisis or typhoid fever, and is then to be regarded as of serious import. A very fatal form occasionally attacks new-born infants, particularly in the first four weeks of their lives. In epidemics of puerperal fever this form of erysipelas has been specially found to prevail.
The treatment of erysipelas is best conducted on the expectant system. The disease in most instances tends to a favourable termination; and beyond attention to the condition of the stomach and bowels, which may require the use of some gentle laxative, little is necessary in the way of medicine. The employment of preparations of iron in large doses is strongly recommended by many physicians. But the chief point is the administration of abundant nourishment in a light and digestible form. Of the many local applications which may be employed, hot fomentations will be found among the most soothing. Dusting the affected part with powdered starch, and wrapping it in cotton wadding, is also of use.
In the case of phlegmonous erysipelas complicating wounds, free incisions into the part are necessary.
ERYTHRAE [mod. Litri], one of the Ionian cities of Asia Minor, situated on a small peninsula stretching into the Bay of Erythrae, at an equal distance from the mountains Mimas and Corycus, and directly opposite the island of Chios. In the peninsula excellent wine was produced. The town was said to have been founded by Ionians under Knopos, son of Codrus. Never a large city, it sent only eight ships to the battle of Lade. The Erythraeans owned for a considerable time the supremacy of Athens, but towards the close of the Peloponnesian war they threw off their allegiance to that city. After the battle of Cnidus, however, they received Conon, and paid him honours in an inscription, still extant. Erythrae was the birthplace of two prophetesses—one of whom, Sibylla, is mentioned by Strabo as living in the early period of the city; the other, Athenais, lived in the time of Alexander the Great. The ruins include well-preserved Hellenistic walls with towers, of which five are still visible. The acropolis (280 ft.) has the theatre on its N. slope, and eastwards lie many remains of Byzantine buildings. Modern Litri is a considerable place and port, extending from the ancient harbour to the acropolis. The smaller coasting steamers call, and there is an active trade with Chios and Smyrna.
ERYTHRITE, the name given to (1) a mineral composed of a hydrated cobalt arsenate, and (2) in chemistry, a tetrahydric alcohol. (1) The mineral erythrite has the formula Co3(AsO4)2·8H2O, and crystallizes in the monoclinic system and is isomorphous with vivianite. It sometimes occurs as beautiful radially-arranged groups of blade-shaped crystals with a bright crimson colour and brilliant lustre. On exposure to light the colour and lustre deteriorate. There is a perfect cleavage parallel to the plane of symmetry, on which the lustre is pearly. Cleavage flakes are soft (H = 2), sectile and flexible; specific gravity 2.95. The mineral is, however, more often found as an earthy encrustation with a peach-blossom colour, and in this form was early (1727) known as cobalt-bloom (Ger. Kobaltblüthe). The name erythrite, from ἐρυθρός, “red,” was given by F.S. Beudant in 1382. Erythrite occurs as a product of alteration of smaltite (CoAs2) and other cobaltiferous arsenides. The finest crystallized specimens are from Schneeberg in Saxony. The earthy variety has been found in Thuringia and Cornwall and some other places. (2) The alcohol erythrite has the constitutional formula HO·H2C·CH(OH)·CH(OH)·CH2OH; it is also known as erythrol, erythroglucin and phycite. It corresponds to tartaric acid, and, like this substance, it occurs in four stereo-isomeric forms. The internally compensated modification, i-erythrite, corresponding to mesotartaric acid, occurs free in the algae Protococcus vulgaris, and as the orsellinate, erythrin, C4H6(OH)2(O·C8H7O3)2, in many lichens and algae, especially Roccella montagnei. It has a sweet taste, melts at 126°, and boils at 330°. Careful oxidation with dilute nitric acid gives erythrose or tetrose, which is probably a mixture of a trioxyaldehyde and trioxyketone. Energetic oxidation gives erythritic acid and mesotartaric acid. i-Erythrite and the racemic mixture of the dextro and laevo varieties were synthesized by Griner in 1893 from divinyl.