2. With CuSO4.
19 November. The mixture, which had been applied to a smooth spot of skin on the forearm, was removed with a 2 percent solution of copper-sulphate. There appeared a blackish-brownish, strongly viscous mass with a metallic sheen which, when rubbed off, spread over the entire experimentation area. After an initial formation of black smoke (phosphorus fumes) and a strong glow, the phosphorescence, because of the formation of a copper-phosphate coating, ceased almost immediately. It seems to be possible that phosphorus, if it comes in contact with small skin wounds, is assimilated into the body by resorption. This spot of skin likewise showed an increase in temperature until 14 December.
3. With water.
19 November. It was always possible to remove the mixture from the skin by water. However, in this case pronounced phosphorescence lasting several minutes and phosphorus fumes were to be observed.
II. Lighting of the phosphorus-caoutchouc mixture and treatment:
1. With R 17.
a. Immediate ignition.
25 November. The mixture was applied to a skin area of 6 × 3 cm. and immediately ignited. After burning for 20 seconds, it was extinguished with water and then wiped off with R 17. A burn appeared, with a yellowish induration of the skin. Later a thin scab formed. After 3 days, the wound was treated with liquid echinacine. On 11 December the scab fell off; the surface of the wound was dry and rosy red. Epithelium formed very rapidly; on 21 December only 1/5 of the surface remained without epithelium. On 29 December this spot too was almost healed.
25 November. The mixture was applied to a skin area of the same size (6 × 3 cm.) and immediately ignited. It burned for 55 seconds until it went out by itself. The burned spot was wiped off with R 17. There appeared a yellowish-brown burn which exhibited a cavity at the proximal end and a blister at the distal end. An elastic scab formed. On the fourth day the wound was treated with echinacine ointment. Thereupon, on 3 December, the scab began to slough off; on 10 December the wound was dry and closed; on 13 December only the edge of the wound still showed a scab and the main part of the wound was covered with fine granulation. The wound continued to become smaller until 29 December without healing over.
b. Ignition after 30 seconds.