Dec. 12.—A cat was anesthetized with ether at 3.45 and the left sciatic nerve was bared. Decerebration was completed at 3.57. The clotting time of the blood began to be tested six minutes later:

4.034minutes
.083.5
.133.5
.184.5
.23 to .25Stimulation of left sciatic.
4.262.5minutes
.293.5
.344
.405
.45 to .50Stimulation of left sciatic.
4.532.5minutes
.577
5.067.5
.15 to .17Stimulation of left sciatic.
5.174minutes
.224.5
.275.5
.365.5
.467

The results obtained in this case, which were similar to results in other cases, are represented graphically in [Fig. 32]. The coagulation time was becoming gradually more prolonged, but each excitation of the sciatic nerve was followed by a marked shortening. The strength of stimulation was not determined with exactness, but it is worthy of note that the current used in the first and the third stimulations was weaker than could be felt on the tongue, whereas that used in the second was considerably stronger, though it did not produce reflex spasms.

Figure 32.—Three shortenings of coagulation time after stimulation of the left sciatic nerve, at 4:23-:25, at 4:45-:50 (stronger), and at 5:15-:17.

Mere tying of the nerve is capable of producing a marked shortening of coagulation, as the following figures show:

Oct. 21.—10.57 cat under ether, and urethane given:

11.118.5minutes
.238.5
.32 to .35Left sciatic bared and tied.
.371.5minutes
.415.5
.507
12.028.5

Stimulation of the crural nerve had similar effects, reducing the clotting time in one instance from a succession of 3, 3, and 3.5 minutes to 1.5 minutes shortly after the application of the current, with a return to 3.5 minutes at the next test.

Operative procedures performed under light anesthesia (i. e., with the more persistent reflexes still present), or reduction of anesthesia soon after operation, resulted in a remarkable shortening of the coagulation time: