Nov. 8.—A cat was etherized and tracheotomized. The abdomen was then opened and a ligature was drawn around the hepatic nerves. The operation was completed at 2.25. At 2.50 the etherization became light and the rate of clotting began to be faster:
| 2.50 | 6 | minutes |
| 3.00 | 5.5 | “ |
| .10 | 3.5 | “ |
| .15 | 3.5 | “ |
| .20 | 4.5 | “ |
| .30 | 7.5 | “ |
Nov. 11.—A female cat, very quiet, was placed in the holder at 1.55. The animal was not excited. At 2.10 etherization was begun; the animal was then tracheotomized, and the femoral artery was exposed.
| 2.21 | 4.5 | minutes | |
| .26 | 4.5 | “ | Anesthesia lessened. |
| .32 | 3.5 | “ | “ light. |
| .35 | Abdomen opened. | ||
| .47 | 1.5 | minutes. | |
| .52 | 1 | “ | |
| .55 | Ligature passed around hepatic nerves. | ||
| .57 | 1.5 | minutes. | Anesthesia light; corneal reflex present. |
| 3.02 | 3 | “ | |
| .07 | 3 | “ | Some hepatic nerves cut. |
| .12 | 4.5 | “ | Rest of hepatic nerves cut. |
| .22 | 5 | “ | |
The results of this experiment are shown graphically in [Fig. 33].
Figure 33.—Shortening of coagulation time during an operation under light anesthesia. At 2:35 the abdomen was opened, at 2:55 a ligature was passed around the hepatic nerves.
Nov. 13.—A cat was etherized at 1.55, tracheotomized, and the femoral artery laid bare. As soon as these preparations were completed, the ether was removed and anesthesia became light. The blood clotted thus:
| 2.08 | 6 | minutes | |
| .15 | 4 | “ | Anesthesia light. |
| .20 | 2 | “ | |
| .24 | 1 | “ | Etherization begun again. |
| .27 | 2.5 | “ | |
| .30 | 3.5 | “ | |
| .35 | 5.5 | “ | |
| .50 | 5.5 | “ |
In the foregoing and in other similar instances, a condition of surgical injury, whether just made or being made, was accompanied by more rapid clotting of blood when the degree of anesthesia was lessened. This condition was one which, if allowed to go further in the same direction, would result in pain. Both direct electrical stimulation and also surgical operation of a nature to give pain in the unanesthetized animal result, therefore, in faster clotting.