November 17: 1.15 p. m., 20 cc 2 per cent caffein (290 mg per kilo) administered by the mouth; 4.30 p. m., some hypersensitiveness, but no other symptoms.
November 18: 9 a. m., urine collected, no reduction of Fehling's solution; no symptoms; rabbit survived.
Rabbit 249. Belgian hare. Weight, 890 grams. Diet, oats.
November 17: 1.30 p. m., 14.5 cc 2 per cent caffein (325 mg per kilo) administered; 4.30 p. m., hypersensitiveness; no other symptoms.
November 18: 10 a. m., no symptoms; urine collected, no reduction; rabbit survived.
Series B.
The object of these experiments was to determine the minimum fatal dose of caffein in the two varieties of rabbits, the white and the gray. All of the animals selected were approximately of the same weight.
Rabbit 239. Belgian hare, male. Weight, 935 grams. Diet, oats.
November 19: 4 p. m., 17 cc 2 per cent caffein (363 mg per kilo) administered by mouth, followed by 10 cc of 0.9 per cent salt solution.