October 6: 11.40 a. m., 5.8 cc 2 per cent caffein injected subcutaneously; 12 noon, reflexes increased, but not as much as in No. 68; 4.20 p. m., guinea pig hypersensitive, reflexes increased more than at 12 noon.

October 7: 9 a. m., alive.

October 15: 9 a. m., found dead.

Guinea pig 61. Brown and black female. Weight, 330 grams. Diet, oats.

October 3: 4 p. m., 4 cc 2 per cent caffein (240 mg per kilo) injected subcutaneously; 5.30 p. m., reflexes increased; runs, but drags posterior extremities.

October 4: 8.50 a. m., found dead.

Guinea pig 62. White, yellow, and black female. Weight, 335 grams. Diet, oats.

October 3: 4.05 p. m., 4 cc 2 per cent caffein (238 mg per kilo) injected subcutaneously in the back; 5 p. m., convulsions; 5.20 p. m., convulsions, alternating with paralysis of anterior and posterior extremities.

October 4: 8.50 a. m., found dead.

Guinea pig 70. White and brown male. Weight, 545 grams. Diet, oats.