Guinea pig 137. White and brown male. Weight, 925 grams. Diet, oats and hay.

June 9: 4 p. m., 7 cc 2 per cent solution caffein injected subcutaneously; 4.50 p. m., reflexes increased.

June 10: Reflexes less marked than at 5 p. m. previous day, but is more sensitive than normal guinea pig, about 10 cc urine passed since injection of caffein, moderate amount of reduction of Fehling's solution.

June 13: Guinea pig alive, appetite good, condition good.

June 16: 9 a. m., found dead.

Guinea pig 135. White and black male. Weight, 955 grams. Diet, hay and oats.

June 9: 3 p. m., 7.5 cc 2 per cent caffein solution given by mouth through stomach tube; 4.50 p. m., reflexes increased.

June 10: Reflexes less than on previous day and less marked than in No. 136, a few cubic centimeters dirty brown urine collected but could not be tested for reduction.

June 13: Condition good, appetite good.

June 16: 9 a. m., found dead.