Rabbit 173. Carrots were fed from October 1 to 18 and oats for the remainder of the experiment.
| Date. | Weight. | Caffein per kilo. | Date. | Weight. | Caffein per kilo. | |
|---|---|---|---|---|---|---|
| Grams. | Gram. | Grams. | Gram. | |||
| Oct. 9 | 1,980 | 0.141 | Oct. 16 | 2,005 | 0.220 | |
| Oct. 11 | 1,905 | .190 | Oct. 18 | 1,845 | ||
| Oct. 13 | 1,930 | .207 | Oct. 20 | 1,740 | .230 |
October 21: Paralysis of posterior extremities.
October 22: 9 a. m., found dead.
The urine was examined before and after the administration of caffein. No symptoms were observed after the administration of caffein (5 doses in 11 days), nor was albumen or sugar found in the urine after any of the experiments on this rabbit. Autopsy: Pyloric mucosa exhibited several ulcers; small intestines showed slight inflammation; liver deeply congested; kidneys showed marked inflammation of cortex; other organs practically normal.
Rabbit 181. Diet, carrots September 29-October 17, then oats.
| Date. | Weight. | Caffein per kilo. | Date. | Weight. | Caffein per kilo. | |
|---|---|---|---|---|---|---|
| Grams. | Gram. | Grams. | Gram. | |||
| Oct. 4 | 1,425 | 0.105 | Oct. 11 | 1,370 | 0.175 | |
| Oct. 5 | 1,450 | .100 | Oct. 13 | 1,385 | .180 | |
| Oct. 6 | 1,270 | .100 | Oct. 16 | 1,345 | .200 | |
| Oct. 7 | 1,210 | .100 | Oct. 17 | 1,030 | ||
| Oct. 8 | 1,375 | .130 | Oct. 18 | 1,230 | ||
| Oct. 9 | 1,305 | .153 | Oct. 20 | 1,215 |
Rabbit was markedly emaciated and weak. No albumen or sugar found in the urine as a result of caffein feeding.
Rabbit 182. Diet of carrots from September 29.
Received caffein subcutaneously as follows: