In diseases we also see these varieties. Who does not know that some particular parts of the skin are especially the seat of some particular cutaneous affections, and that when these affections are general, they always predominate in certain places. We ought not to be astonished at these varieties, since we have seen that the dermoid texture is infinitely variable as it respects its papillæ, its reticular body, its chorion, &c.

Second Character. Intermission in one relation; continuity in another.

The life of the cutaneous system is essentially intermittent in relation to animal sensibility. All the senses exhibit this phenomenon. Thus when the eye has for a long time gazed upon objects, the ear heard sounds, the nose received odours, and the mouth tastes, these different organs become unfit to receive new sensations; they become fatigued, and require rest to regain their forces. It is the same with regard to feeling and the touch; wearied by the impression of surrounding bodies, the skin requires an intermission of action to regain excitability adapted to new impressions. We know that a short time before sleep, external bodies produce but an obscure sensation upon it, and that their contact has no effect in this state, in which animals seem to lose half of their existence. The more powerfully the cutaneous sensibility has been excited, the more profound is sleep; hence why all painful exercises, great frictions, &c. are always followed by a deep sleep. Yet this sense can sometimes exert itself, while the others sleep; pinch the leg of a man asleep; he draws it away without waking, and has afterwards no remembrance of the sensation. Thus somnambulists often hear sounds, even eat, &c.; for, as I have said elsewhere, sleep may affect but a very limited part of animal life, as it may the whole.

Under the relation of organic sensibility, the life of the cutaneous system is essentially continuous. Thus the functions over which this property presides have a character opposite to the preceding. The insensible transpiration takes place continually, though there may be some periods in which it is more active than in others. The oily fluid is incessantly carried away and renewed; we might even say sometimes that it is when the animal sensibility is interrupted, that the organic is in the greatest exercise.

It is especially in diseases that they have made this observation, which is besides generally applicable to organic life. All this life is as active and even more so during the night than during the day. Most of the diseases that attack the functions which belong to it, are marked by an increase of activity during the night. All fevers which particularly affect the circulation have their exacerbation towards night. In diseases of the heart, the patients are more oppressed at this period, &c. In phthisis which affects respiration, it is in the night especially that there is hectic fever, sweats, &c. Pneumonia and pleurisy, exhibit frequent exacerbations towards night. In glandular diseases, either acute or chronic we make the same observation. It would be necessary to refer to almost all the affections which alter especially an organic function, in order to omit nothing upon this point. On the contrary, observe hemiplegia, epilepsy, convulsions, various paralysies of the different organs of sense, most mental alienations, apoplexy and other affections which exert their influence more particularly upon animal life, they have not, so often at least, their exacerbations towards evening and during the night, no doubt because in the natural state, this life is in the habit of becoming drowsy and not of being raised like the other which seems to imprint this character upon its alterations. Other causes no doubt have an influence upon this phenomenon; but I believe this to be a real one.

Third Character. Influence of the Sexes.

The sex has an influence upon the cutaneous life. In general the animal portion of this life is more raised in women, in whom every thing that belongs to the sensations is proportionally more marked than in man, who predominates by the power of his locomotive muscles. The effects of tickling are infinitely more powerful in females. All the arts which require nicety and delicacy of touch are advantageously cultivated by women. The peculiar texture of the chorion, a texture generally more delicate, has no doubt an influence upon this phenomenon. As to the organic portion of the cutaneous life, the difference is not very great. Man appears to be superior in this respect; he generally sweats more; his skin is more unctuous, which proves a greater secretion.

Fourth Character. Influence of Temperament.

The temperament peculiar to each individual is not a less real cause of differences in the skin. We know that the colour, roughness and pliability of this organ vary according as individuals are sanguineous, phlegmatic, &c. that these external attributes are even a character of the temperaments. Varieties of structure no doubt coincide with these. Is it then astonishing that the animal sensibility differs so much, that the touch itself should be delicate in some and dull in others, that some should be very ticklish, whilst others are not so at all, &c.? Ought we to be astonished if the organic sensibility, which is very variable, should determine, according to the individuals, many varieties in the phenomena over which it presides; if in some, it allows much blood to go to the face, and if it repels this fluid in others who are always pale; if some men sweat much, whilst others have the skin almost always dry; if the cutaneous oil varies in quantity; if there are some skins much disposed to eruptions, either acute or chronic, to pimples of different natures, and if others are almost always free from them, even when the individuals expose themselves to the contagion of these diseases; if superficial wounds, of the same extent and made by the same instrument, are sometimes quicker and sometimes slower in healing; if the cure of cutaneous diseases is also very variable in its periods, &c. &c.?