Francisco Antonio de Bances y López-Candamo was a playwright of the Spanish Golden Age.

Francisco Bauzá (1849–1899) was a Uruguayan political figure and historian.

Francisco Bilbao Barquín was a Chilean writer, philosopher and liberal politician.

Francisco Brines Bañó was a Spanish poet.

Francisco Calvo Serraller was a Spanish art historian.

Francisco Camprodón y Safont was a Spanish playwright, poet, politician and librettist, originally from Catalonia.

Francisco Cascales (1564–1642) was a Spanish erudite, humanist and writer. He wrote Discurso de la ciudad de Cartagena.

Francisco V. Coching was a Filipino comic books illustrator and writer and is regarded as one of the “pillars of the Philippine Komiks Industry”. He served as both illustrator and writer for his comic book stories, Coching is referred to as the "King of Komiks", and as the "Dean of Philippine Comics". In 2014, he was posthumously conferred as a National Artist for Visual Arts, the highest honor for artists in the Philippines.

Francisco Coloane Cárdenas was a Chilean novelist and short fiction writer whose works have been translated into many languages. Some of his books were adapted to theatre and film.

Francisco de Moraes Cabral, also spelled Francisco de Morais Cabral, was a Portuguese writer. Born in Bragança, he served as personal secretary to the Portuguese ambassador in France, and composed, during two voyages to Paris, a chivalric romance called Palmeirim de Inglaterra; Palmerin of England), a "spin-off" of the popular Amadís de Gaula series.