5. Time of Injection:
Between 8 and 10 A. M. (Bandelier and Roepke).
Late in the evening, 9 or 10 P. M., or later (others).
6. Dose:
According to Koch: Begin with 1⁄2 mg., or 1 mg., according to condition of patient; give larger dose if no reaction. Order of increase: 1 mg.; 5 mg.; 10 mg. (last dose repeated if necessary).
Interval between injections: two or three days.
Present Usage: First dose in adults, 1⁄2 mg., or 1⁄5 mg., or smaller, according to physical condition.
First dose in children: 1⁄10 mg., or 1⁄20 mg., or even smaller.
Thus, in adults: 1⁄2, or 1, 3, 5, 8, and rarely 10;
In children: 1⁄10, 1⁄2, 1, 3.