The King received the information very graciously, observing in reply, that although he had never made any suggestion of the kind, he had "often thought upon the subject." The royal command was of course at once transmitted, that the dignity should be accepted. By special favor, moreover, the Pope dispensed the new Cardinal from the duty of going to Rome in person, and despatched his chamberlain, Theophilus Friso, to Brussels, with the red hat and tabbard.

The prelate, having thus reached the dignity to which he had long aspired, did not grow more humble in his deportment, or less zealous in the work through which he had already gained so much wealth and preferment. His conduct with regard to the edicts and bishoprics had already brought him into relations which were far from amicable with his colleagues in the council. More and more he began to take the control of affairs into his own hand. The consulta, or secret committee of the state council, constituted the real government of the country. Here the most important affairs were decided upon without the concurrence of the other seignors, Orange, Egmont, and Glayon, who, at the same time, were held responsible for the action of government. The Cardinal was smooth in manner, plausible of speech, generally even-tempered, but he was overbearing and blandly insolent. Accustomed to control royal personages, under the garb of extreme obsequiousness, he began, in his intercourse with those of less exalted rank, to omit a portion of the subserviency while claiming a still more undisguised authority. To nobles like Egmont and Orange, who looked down upon the son of Nicolas Perrenot and Nicola Bonvalot as a person immeasurably beneath themselves in the social hierarchy, this conduct was sufficiently irritating. The Cardinal, placed as far above Philip, and even Margaret, in mental power as he was beneath them in worldly station, found it comparatively easy to deal with them amicably. With such a man as Egmont, it was impossible for the churchman to maintain friendly relations. The Count, who notwithstanding his romantic appearance, his brilliant exploits, and his interesting destiny, was but a commonplace character, soon conceived a mortal aversion to Granvelle. A rude soldier, entertaining no respect for science or letters, ignorant and overbearing, he was not the man to submit to the airs of superiority which pierced daily more and more decidedly through the conventional exterior of the Cardinal. Granvelle, on the other hand, entertained a gentle contempt for Egmont, which manifested itself in all his private letters to the King, and was sufficiently obvious in his deportment. There had also been distinct causes of animosity between them. The governorship of Hesdin having become vacant, Egmont, backed by Orange and other nobles, had demanded it for the Count de Roeulx, a gentleman of the Croy family, who, as well as his father, had rendered many important services to the crown. The appointment was, however, bestowed, through Granvelle's influence, upon the Seigneur d'Helfault, a gentleman of mediocre station and character, who was thought to possess no claims whatever to the office. Egmont, moreover, desired the abbey of Trulle for a poor relation of his own; but the Cardinal, to whom nothing in this way ever came amiss, had already obtained the King's permission to, appropriate the abbey to himself Egmont was now furious against the prelate, and omitted no opportunity of expressing his aversion, both in his presence and behind his back. On one occasion, at least, his wrath exploded in something more than words. Exasperated by Granvelle's polished insolence in reply to his own violent language, he drew his dagger upon him in the presence of the Regent herself, "and," says a contemporary, "would certainly have sent the Cardinal into the next world had he not been forcibly restrained by the Prince of Orange and other persons present, who warmly represented to him that such griefs were to be settled by deliberate advice, not by choler." At the same time, while scenes like these were occurring in the very bosom of the state council, Granvelle, in his confidential letters to secretary Perez, asserted warmly that all reports of a want of harmony between himself and the other seignors and councillors were false, and that the best relations existed among them all. It was not his intention, before it should be necessary, to let the King doubt his ability to govern the counsel according to the secret commission with which he had been invested.

His relations with Orange were longer in changing from friendship to open hostility. In the Prince the Cardinal met his match. He found himself confronted by an intellect as subtle, an experience as fertile in expedients, a temper as even, and a disposition sometimes as haughty as his own. He never affected to undervalue the mind of Orange. "'Tis a man of profound genius, vast ambition—dangerous, acute, politic," he wrote to the King at a very early period. The original relations between himself and the Prince bad been very amicable. It hardly needed the prelate's great penetration to be aware that the friendship of so exalted a personage as the youthful heir to the principality of Orange, and to the vast possessions of the Chalons-Nassau house in Burgundy and the Netherlands, would be advantageous to the ambitious son of the Burgundian Councillor Granvelle. The young man was the favorite of the Emperor from boyhood; his high rank, and his remarkable talents marked him indisputably for one of the foremost men of the coming reign. Therefore it was politic in Perrenot to seize every opportunity of making himself useful to the Prince. He busied himself with securing, so far as it might be necessary to secure, the succession of William to his cousin's principality. It seems somewhat ludicrous for a merit to be made not only for Granvelle but for the Emperor, that the Prince should have been allowed to take an inheritance which the will of Rene de Nassau most unequivocally conferred, and which no living creature disputed. Yet, because some of the crown lawyers had propounded the dogma that "the son Of a heretic ought not to succeed," it was gravely stated as an immense act of clemency upon the part of Charles the Fifth that he had not confiscated the whole of the young Prince's heritage. In return Granvelle's brother Jerome had obtained the governorship of the youth, upon whose majority he had received an honorable military appointment from his attached pupil. The prelate had afterwards recommended the marriage with the Count de Buren's heiress, and had used his influence with the Emperor to overcome certain objections entertained by Charles, that the Prince, by this great accession of wealth, might be growing too powerful. On the other hand, there were always many poor relations and dependents of Granvelle, eager to be benefitted by Orange's patronage, who lived in the Prince's household, or received handsome appointments from his generosity. Thus, there had been great intimacy, founded upon various benefits mutually conferred; for it could hardly be asserted that the debt of friendship was wholly upon one side.

When Orange arrived in Brussels from a journey, he would go to the bishop's before alighting at his own house. When the churchman visited the Prince, he entered his bed-chamber without ceremony before he had risen; for it was William's custom, through life, to receive intimate acquaintances, and even to attend to important negotiations of state, while still in bed.

The show of this intimacy had lasted longer than its substance. Granvelle was the most politic of men, and the Prince had not served his apprenticeship at the court of Charles the Fifth to lay himself bare prematurely to the criticism or the animosity of the Cardinal with the recklessness of Horn and Egmont. An explosion came at last, however, and very soon after an exceedingly amicable correspondence between the two upon the subject of an edict of religious amnesty which Orange was preparing for his principality, and which Granvelle had recommended him not to make too lenient. A few weeks after this, the Antwerp magistracy was to be renewed. The Prince, as hereditary burgrave of that city, was entitled to a large share of the appointing power in these political arrangements, which at the moment were of great importance. The citizens of Antwerp were in a state of excitement on the subject of the new bishops. They openly, and in the event, successfully resisted the installation of the new prelate for whom their city had been constituted a diocese. The Prince was known to be opposed to the measure, and to the whole system of ecclesiastical persecution. When the nominations for the new magistracy came before the Regent, she disposed of the whole matter in the secret consulta, without the knowledge, and in a manner opposed to the views of Orange. He was then furnished with a list of the new magistrates, and was informed that he had been selected as commissioner along with Count Aremberg, to see that the appointments were carried into effect. The indignation of the Prince was extreme. He had already taken offence at some insolent expressions upon this topic, which the Cardinal had permitted himself. He now sent back the commission to the Duchess, adding, it was said, that he was not her lackey, and that she might send some one else with her errands. The words were repeated in the state council. There was a violent altercation—Orange vehemently resenting his appointment merely to carry out decisions in which he claimed an original voice. His ancestors, he said, had often changed the whole of the Antwerp magistracy by their own authority. It was a little too much that this matter, as well as every other state affair, should be controlled by the secret committee of which the Cardinal was the chief. Granvelle, on his side, was also in a rage. He flung from the council-chamber, summoned the Chancellor of Brabant, and demanded, amid bitter execrations against Orange, what common and obscure gentleman there might be, whom he could appoint to execute the commission thus refused by the Prince and by Aremberg. He vowed that in all important matters he would, on future occasions, make use of nobles less inflated by pride, and more tractable than such grand seignors. The chancellor tried in vain to appease the churchman's wrath, representing that the city of Antwerp would be highly offended at the turn things were taking, and offering his services to induce the withdrawal, on the part of the Prince, of the language which had given so much offence. The Cardinal was inexorable and peremptory. "I will have nothing to do with the Prince, Master Chancellor," said he, "and these are matters which concern you not." Thus the conversation ended, and thus began the open state of hostilities between the great nobles and the Cardinal, which had been brooding so long.

On the 23rd July, 1561, a few weeks after the scenes lately described, the Count of Egmont and the Prince of Orange addressed a joint letter to the King. They reminded him in this despatch that, they had originally been reluctant to take office in the state council, on account of their previous experience of the manner in which business had been conducted during the administration of the Duke of Savoy. They had feared that important matters of state might be transacted without their concurrence. The King had, however, assured them, when in Zeland, that all affairs would be uniformly treated in full council. If the contrary should ever prove the case, he had desired them to give him information to that effect, that he might instantly apply the remedy. They accordingly now gave him that information. They were consulted upon small matters: momentous affairs were decided upon in their absence. Still they would not even now have complained had not Cardinal Granvelle declared that all the members of the state council were to be held responsible for its measures, whether they were present at its decisions or not. Not liking such responsibility, they requested the King either to accept their resignation or to give orders that all affairs should be communicated to the whole board and deliberated upon by all the councillors.

In a private letter, written some weeks later (August 15), Egmont begged secretary Erasso to assure the King that their joint letter had not been dictated by passion, but by zeal for his service. It was impossible, he said, to imagine the insolence of the Cardinal, nor to form an idea of the absolute authority which he arrogated.

In truth, Granvelle, with all his keenness, could not see that Orange, Egmont, Berghen, Montigny and the rest, were no longer pages and young captains of cavalry, while he was the politician and the statesman. By six or seven years the senior of Egmont, and by sixteen years of Orange, he did not divest himself of the superciliousness of superior wisdom, not unjust nor so irritating when they had all been boys. In his deportment towards them, and in the whole tone of his private correspondence with Philip, there was revealed, almost in spite of himself, an affectation of authority, against which Egmont rebelled and which the Prince was not the man to acknowledge. Philip answered the letter of the two nobles in his usual procrastinating manner. The Count of Horn, who was about leaving Spain (whither he had accompanied the King) for the Netherlands, would be entrusted with the resolution which he should think proper to take upon the subject suggested. In the mean time, he assured them that he did not doubt their zeal in his service.

As to Count Horn, Granvelle had already prejudiced the King against him. Horn and the Cardinal had never been friends. A brother of the prelate had been an aspirant for the hand of the Admiral's sister, and had been somewhat contemptuously rejected. Horn, a bold, vehement, and not very good-tempered personage, had long kept no terms with Granvelle, and did not pretend a friendship which he had never felt. Granvelle had just written to instruct the King that Horn was opposed bitterly to that measure which was nearest the King's heart—the new bishoprics. He had been using strong language, according to the Cardinal, in opposition to the scheme, while still in Spain. He therefore advised that his Majesty, concealing, of course, the source of the information, and speaking as it were out of the royal mind itself, should expostulate with the Admiral upon the subject. Thus prompted, Philip was in no gracious humor when he received Count Horn, then about to leave Madrid for the Netherlands, and to take with him the King's promised answer to the communication of Orange and Egmont. His Majesty had rarely been known to exhibit so much anger towards any person as he manifested upon that occasion. After a few words from the Admiral, in which he expressed his sympathy with the other Netherland nobles, and his aversion to Granvelle, in general terms, and in reply to Philip's interrogatories, the King fiercely interrupted him: "What! miserable man!" he vociferated, "you all complain of this Cardinal, and always in vague language. Not one of you, in spite of all my questions, can give me a single reason for your dissatisfaction." With this the royal wrath boiled over in such unequivocal terms that the Admiral changed color, and was so confused with indignation and astonishment, that he was scarcely able to find his way out of the room.

This was the commencement of Granvelle's long mortal combat with Egmont, Horn, and Orange. This was the first answer which the seignors were to receive to their remonstrances against the churchman's arrogance. Philip was enraged that any opposition should be made to his coercive measures, particularly to the new bishoprics, the "holy work" which the Cardinal was ready, to "consecrate his fortune and his blood" to advance. Granvelle fed his master's anger by constant communications as to the efforts made by distinguished individuals to delay the execution of the scheme. Assonville had informed him, he wrote, that much complaint had been made on the subject by several gentlemen, at a supper of Count Egmont's. It was said that the King ought to have consulted them all, and the state councillors especially. The present nominees to the new episcopates were good enough, but it would be found, they said, that very improper personages would be afterwards appointed. The estates ought not to permit the execution of the scheme. In short, continued Granvelle, "there is the same kind of talk which brought about the recall of the Spanish troops." A few months later, he wrote to inform Philip that a petition against the new bishoprics was about to be drawn up by "the two lords.". They had two motives; according to the Cardinal, for this step—first, to let the King know that he could do nothing without their permission; secondly, because in the states' assembly they were then the cocks of the walk. They did not choose, therefore, that in the clerical branch of the estates any body should be above the abbots, whom they could frighten into doing whatever they chose. At the end, of the year, Granvelle again wrote to instruct his sovereign how to reply to the letter which was about to be addressed to him by the Prince of Orange and the Marquis Berghen on the subject of the bishoprics. They would tell him, he said, that the incorporation of the Brabant abbeys into the new bishoprics was contrary to the constitution of the "joyful entrance." Philip was, however, to make answer that he had consulted the universities, and those learned in the laws, and had satisfied himself that it was entirely constitutional. He was therefore advised to send his command that the Prince and Marquis should use all their influence to promote the success of the measure. Thus fortified, the King was enabled not only to deal with the petition of the nobles, but also with the deputies from the estates of Brabant, who arrived about this time at Madrid. To these envoys, who asked for the appointment of royal commissioners, with whom they might treat on the subject of the bishoprics, the abbeys, and the "joyful entrance," the King answered proudly, "that in matters which concerned the service of God, he was his own commissioner." He afterwards, accordingly, recited to them, with great accuracy, the lesson which he had privately received from the ubiquitous Cardinal. Philip was determined that no remonstrance from great nobles or from private citizens should interfere with the thorough execution of the grand scheme on which he was resolved, and of which the new bishoprics formed an important part. Opposition irritated him more and more, till his hatred of the opponents became deadly; but it, at the same time, confirmed him in his purpose. "'Tis no time to temporize," he wrote to Granvelle; "we must inflict chastisement with full rigor and severity. These rascals can only be made to do right through fear, and not always even by that means."