“Chest.—Right pleura presents a few slight adhesions near the middle; left pleura free. No fluid in either pleural cavity. Pericardium contained about half an ounce of serum, and presented a few opaque patches on its surface. Both sides of heart contained blood, the right side rather more than the left. Blood more than usually fluid. External fat of heart considerable, about three lines on some parts of right ventricle. Muscular tissue of heart generally flabby, and rather pale, but not distinctly disorganized to the naked eye. Valves perfectly healthy. Aorta presented very faint traces of atheroma. A few traces of atrophy of right lung towards its apex and anterior edge, but very limited. In all other respects lungs free from disease, but somewhat congested.
“Spleen soft, but not diffluent.
“Liver congested, but otherwise normal.
“Kidneys congested, but otherwise healthy.
“Brain.—The subarachnoid fluid presents considerable milky opacity, and is of moderate quantity. Moderate congestion of the meninges generally. About half an ounce of fluid in the ventricles. Substance of brain healthy. Arteries at base perfectly free from atheroma. Air passages.—Glottis perfectly patent. Mucous membrane of larynx and trachea slightly congested.
“Microscopic examination shewed the fibres of the heart to be nearly normal, though scarcely so distinctly striated as in some cases. The minute vessels of the brain and pia mater presented at some points a few clustering granules, but to no great extent.”[[101]]
Dr. Dunsmure expressed the opinion that four or five minutes elapsed from the time the chloroform was left off before the pulse failed. But it is pretty certain that he has much over-estimated the time. Indeed, if the shaving of the perineum were likely to occupy even half of this time, the operator would have done it, or had it done, before the chloroform was administered. Dr. Dunsmure makes the following remark in his comments on the case: “In several instances where I have seen chloroform very nearly prove fatal, the respiration became gradually restored after an inspiration had once been made; in this case, however, no such fortunate occurrence took place.” In the other cases to which allusion is here made, the heart has not been paralysed, or at least not completely, but they show that the method of administering chloroform in Edinburgh had been far from satisfactory in its results, although no patient had before that time been actually lost.[[102]]
Case 33 occurred in University College Hospital, London, and the following account of it was given by Dr. Hillier:
“E. R., aged 40, a woman of moderate height, rather thin. The general health has been pretty good; she had not been liable to palpitation or dyspnœa. Had been in the habit of drinking pretty freely. Admitted on October 5th, at 11 p.m. She was suffering from the symptoms of strangulated hernia, which had existed two days and a half. Efforts were made to reduce the hernia, both without and with a warm bath, in which she was for upwards of half an hour without getting very faint. These efforts being unsuccessful, an operation was at once determined on. Her pulse was at this time regular, and of tolerable strength.
“Chloroform was administered in the usual way, on a piece of lint, which was held three or four inches from the patient’s face, and then brought to within an inch and a half of her nose and mouth, leaving space around for the admission of air.