Sergey V. Arzhanukhin is a Russian philosopher. He is a professor at the Russian Presidential Academy of National Economy and Public Administration and holds a Doctor of Philosophical Sciences. Arzhanukhin is knowledgeable in philosophy and public and political theories of Russian masons.

Sergey Sergeyevich Averintsev was a Russian literary scholar, Byzantinist and Slavist.

Sergey Nikolayevich Baburin is a Russian nationalist politician, member of the State Duma of the first, second and fourth convocations where he served in the Committee on Civil, Criminal, Arbitral and Procedural Law, leader of the Russian All-People's Union and an ex-leader of the Rodina political party. He also served as a rector of the Russian State University of Trade and Economics (RGTEU) from 2002 to 2012.

Sergey Nikolayevich Bagayev is a Russian scientist, a specialist in the field of quantum electronics and laser physics, director of the Institute of Laser Physics (1992–2016). His h-index is 16.

Sergey Vitalyevich Bezrukov is a Soviet and Russian film and stage actor, singer, People's Artist of Russia, the laureate of the State Prize of the Russian Federation. He currently works at Tabakov Studio. He is a member of the Supreme Council of the party United Russia.

Sergey Semyonovich Biryuzov was a Marshal of the Soviet Union and Chief of the General Staff.

Sergey Petrovich Botkin was a famous Russian clinician, therapist, and activist, one of the founders of modern Russian medical science and education. He introduced triage, pathological anatomy, and post mortem diagnostics into Russian medical practice.

Sergey Borisovich Brilyov or Brilev is a Russian television journalist on the state-owned TV channel Rossiya.

Sergey Alexeyevich Chaplygin was a Russian and Soviet physicist, mathematician, and mechanical engineer. He is known for mathematical formulas such as Chaplygin's equation and for a hypothetical substance in cosmology called Chaplygin gas, named after him.

Sergey Nikolayevich "Chizh" Chigrakov is a Russian rock performer and songwriter. Most of his current songs are recorded with his band, Chizh & Co.